Why Type A Blood May Increase Your Risk of COVID-19

The SARS-CoV-2 coronavirus can more easily adhere to cells in the airways of people with type A blood compared to those with type B or O blood, a new study suggests. The findings point to a possible explanation for why, throughout the pandemic, studies have found that people with type A blood are more likely to contract COVID-19 and develop severe symptoms than other blood types.

Laboratory experiments revealed that part of the coronavirus called the “receptor-binding domain” (RBD), which binds directly to cells to drive infection, it also attaches to unique molecules associated with type A blood. These molecules, known as antigens, appear on the cells they coat the respiratory tract, including the lungs, according to the study, published on March 3 in the journal Blood advances.

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