Resistance training, a form of exercise that forces your skeletal muscles to contract, improves the ability of muscles to recycle, according to a recent study. Autophagy is an important catabolic pathway in the cells responsible for the clearance of proteins and organelles. The pathological levels of autophagy are associated with muscle wasting, but physiological levels are important for cell recycling.
In the present study, the indicators of autophagy and expanded protein response (UPR), which is another system to maintain cellular homeostasis, were investigated. muscle biopsies after a single endurance exercise session and after 21 weeks of resistance training in previously untrained young and old men.
"Aging may attenuate some of the positive effects of strength-induced improvement in muscle strength," says Jaakko Hentila and Finnish Academy researcher Juha Hulmi.
However, the investigators reported that the UPR that is induced by the accumulation of misfolded proteins in the endoplasmic reticulum (ER) was activated with unaccustomed resistance exercises regardless of age. Skeletal muscle seems to adapt to resistance exercise in a similar way in young and old people in many ways.
The study was conducted at the University of Jyvaskyla in collaboration with researchers from Oslo.
The results are published in the journal Acta Physiologica. (ANI)
This is published without editing from the ANI feed.
Published: April 9, 2018 1:53 pm