Why are new coronavirus viruses emerging in America?


Nearly a year into the epidemic, Kovid-19 is spreading at record high rates in the United States, and with it, new versions of the virus are emerging. Last week, researchers in Ohio said they had identified two unique variants in Columbus.

Experts believe that it is not surprising that new versions have appeared in the US, but stress that uncontrolled transmission of the virus in the country provides ample opportunities for this. Therefore, the best way, to put a crack on new variants, is to stop the spread, he says.

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“There is only one way [stop emergence of new variants] The spread of the virus is to stop, ”said Ben Bimber, a research professor at the University of Oregon Health and Sciences.

If there are more people infected, then there is simply more virus and more opportunities to mutate it.

“Every time the virus repeats, it’s an opportunity to silence,” he said. “If there are more people infected, there is simply more virus and more opportunities to mutate it.”

When the coronavirus infects a person, it enters the cells and makes copies of itself. “Every time the virus copies itself, there is a chance of introducing errors,” Bimber said. “If the virus is recurring in people, it will slowly accumulate mutations.”

Often, these errors, or mutations, are redundant. But in some cases, they can give the virus the advantage of survival – making it more contagious, for example, or more resistant to treatment or vaccines. On the other hand, some mutations may present vulnerable viruses.

Related: “We do not have a nationally coordinated system to do this at a higher level,” one expert said.

It is unclear how the two recently identified variants in the virus affect the virus.

Findings on those variants were posted on the online preprint server BioRxiv last Friday, meaning they have not yet been peer-reviewed. In the study, researchers analyzed genetic sequences of more than 220 coronovirus samples obtained in the Columbus region from April 2020 to early January 2021.

Variants identified in Ohio contain a mutation on the spike protein of the virus called N501Y – the same infection found in the more infectious UK version, as well as the South African version, Drs. Dan Jones is the vice president of the division of molecular pathology. At the Ohio State University Wexner Medical Center, said during a media briefing Wednesday. The variant did not reach anyone from abroad; Rather, by analyzing other small changes in the variant’s genetic code, researchers were able to determine that it had emerged independently in the US.

William Hainz, an associate professor of epidemiology at the Harvard TH Chan School of Public Health, said he was not surprised to detect one with new variants, especially the N501Y mutation, as it had happened many times. “Apart from emerging in Britain and South Africa, that particular mutation has also been detected in Brazil.

The researchers said the second variant had a combination of three mutations, which had not been seen together before. While the N501Y mutation was found in only one sample, this variant, with three mutations, quickly became prominent in samples tested by researchers in December and January.

Jones told NBC News that vaccination is important to prevent the spread of both variants, as well as reducing the likelihood of new variants coming.

“Your pool is big [susceptible] There is a greater potential for mutations for patients to survive and emerge, ”he said. “It has to be passed from one person to another, so if you are not getting a lot of infection in the population [because of vaccination], Even then a significant mutation may just be out, because the person who was infected does not transmit the virus to anyone else. “

Jones stated, “Despite being pathologically fit in the virus, pathological change does no good work.

The Centers for Disease Control and Prevention said it is “aware” of the Ohio variant, and released the same statement on Jan. 8 following a controversial report from the White House Coronavirus Virus Force, speculating that an American version could be driving is. There has been a recent increase in the country.

That statement said that “it is highly likely that multiple versions are developing simultaneously worldwide,” adding that the CDC “has not seen the emergence of a special edition in the United States as of B.1.1.7. Seen with emergence. In B.1.351 in the United Kingdom or South Africa. “

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However, the statement stated that “there is a strong possibility that there are variants in the United States; however, it may take weeks or months to find out if there is the same type of virus, which is the Kovid-19 Causes which is similar to the boom in the United Kingdom.

New variants are expected and not all a cause for concern, said Angera Rasmussen, a virologist at the Georgetown University Center for Global Health Science and Security.

“We should be concerned when a version is accompanied by epidemiological evidence such as that observed in the UK” – she said, citing an increase in such cases as the country’s version grew more widely – “or If there is an important association for increasing the severity of the disease. “

Rasmussen said, “However, regardless of the different types, we should insist on reducing the transmission of all types. This means wearing masks, avoiding crowds and practicing good hand hygiene.

Bimber agreed that it was too early to draw any conclusions about the variants found in Ohio.

“It’s a really fast-moving place and it takes time to evaluate the effects of the new variants,” he said. “This will not be the last one and there are definitely going to be new versions that emerge in the virus as it infects more individuals.”

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