‘We can’t let our guard down’: Scientists say COVID-19 can spread even if some children have antibodies

As schools and colleges reopen around the country, scientists say that social disturbances are an important public-health response to COVID-19. New research released Thursday sheds more light on children who test positive for COVID-19, and infectivity of coronaviruses. Children often remain asymptomatic or exhibit very few symptoms, and research also provides insight into the course of the disease at a critical time for families and communities.

A study published in the latest edition of the Journal of Pediatrics has found that viruses and antibodies can coexist in young patients. “With most viruses, when you start detecting antibodies, you won’t be able to detect the virus. But with COVID-19, we’re seeing both of them, “says Burak Bahar, lead author of the study of laboratory informatics at Children’s National Hospital in Washington DC.” This means that children still have the ability to transmit antibodies. ” . Has been detected. ”

‘Children still have the ability to infect the virus, even when antibodies have been detected.’

– Director of Laboratory Informatics at Children’s National Hospital in Burak Bahar, Washington DC

The researchers reviewed the analysis of 6,369 children tested for SARS-CoV-2, which causes the virus COVID-19, and 215 patients who underwent antibody testing at Children’s National between March 2020 and June 2020. Of these 215 young patients, 33 were tested positive for both viruses and antibodies during the course of the disease. Nine of those 33 also showed the presence of antibodies in their blood, while the latter tested positive for the virus.
What’s more, researchers found that patients aged 6 to 15 took a longer time (an average time of 32 days) to clear the virus, meaning it had left their system, versus 22 Patients 16 years of age (median age of 18 days) through age. Women in the age group of 6 to 15 take longer to clear the virus than men: an average of 44 days for women vs. 25.5 days for men. “We cannot let our guard down just because a child has antibodies or is not showing symptoms,” Bahar said.

The study also found that 25 days was the average time from viral positivity to negativity – the moment when the virus cannot be detected; It took 18 days to go from viral positivity to seropositivity – or the presence of antibodies in the blood – and 36 days to reach a sufficient level of neutralizing antibodies. These “neutralizing antibodies”, the researchers wrote, are important in protecting a person from re-infection with the same virus.
Four important caveats: First, the study looked at a relatively small number of children. Secondly, the next stage of research will be to test whether coronovirus that is present with antibodies to the disease can be transmitted to others. Third, scientists need to find out if antibodies are correlated with immunity and, fourth, they need to establish how long antibodies and potential protection from reinforcement actually last. As such, Bahr reiterates the need for social distinctions.
related:Dr. Fauci: This is ‘comprehensible’, we will know by November whether a safe, effective vaccine is coming.
A separate study published this week in JAMA Pediatrics suggests that children can spread SARS-CoV-2, even if they never develop symptoms or after the symptoms clear up. This found a significant variation in how long children “shed” the virus through their respiratory tract and, therefore, could possibly be infectious. Researchers also found that the duration of symptoms of COVID-19 also varied widely from three days to about three weeks.
A recent systematic review estimated that 16% of children with SARS-CoV-2 infection are asymptomatic, but evidence suggests that 45% of pediatric infections are asymptomatic, according to the Centers for Disease Control and Prevention. According to the CDC, the signs and symptoms of COVID-19 in children are similar to other infections and non-infectious processes, including influenza.

A separate study in JAMA Pediatrics states that children can spread SARS-CoV-2 even if they never develop symptoms or even longer after the symptoms clear up.

Under pressure from the teachers’ union to delay the start of the school year, New York City Mayor Bill de Blasio announced Tuesday that in-person classes would be pushed back on September 21, 11 days later than planned. Distance education, which was originally started on 10 September, will now start on 16 September. Other countries have not done so well with school reopening. Israel, which reopened schools this week, experienced an outbreak when schools reopened on 17 May.
Bahar also advised teachers and students to wear masks. According to an experiment published Wednesday by the Physics of Fluids, to reduce the risk of an outbreak of COVID-19, it may be better to use high-quality clothing or surgical masks, which is also part of an experiment published Wednesday by Physics Accordingly, instead of masks equipped with face shield and exhaust valves, be of a plain design. A monthly peer reviewed scientific journal incorporating fluid dynamics was first established in 1958 by the American Institute of Physics.
As of Thursday, COVID-19 had infected 26,118,288 people worldwide, accounting for most asymptomatic cases, and 864,801 casualties. According to data collected by Johns Hopkins University, the US still has the highest number of COVID-19 cases in the world (6,131,344 and 186,293 deaths), Brazil (3,997,865), India (3,853,406) and Russia (1,003,923). New York has recorded 436,218 infections and the highest number of deaths (32,972) in the US.
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