Turns out we might need 3 coronavirus vaccines instead of 2, here’s why – BGR


  • As the most contagious COVID variants spread across the US, Pfizer is exploring the usefulness of a third booster dose.
  • Pfizer hopes that a third dose of the vaccine could “increase the antibody response 10 to 20 times.”
  • Pfizer and Moderna plan to boost vaccine production and ship 140 million doses to the US over the next 4.5 weeks.

Pfizer’s coronavirus vaccine is 95% effective in preventing a COVID infection, a staggering number that even surprised the company’s team of researchers. Still, with more contagious variants from the UK and South Africa already spreading in the US, Pfizer is currently investigating what kind of impact a third booster dose would have on the immune system response to COVID. Currently, the Pfizer vaccine requires the administration of two doses separated by three weeks.

According to Pfizer CEO Albert Bourla, the researchers hope that a third booster injection could “increase the antibody response 10 to 20 times.”

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NBC News reports:

The new study will monitor the safety and efficacy of a third dose in two age groups: those 18 to 55 and those 65 to 85. Participants came from a group of people who were among the first to receive the Pfizer-BioNTech vaccine. – People who volunteered for Pfizer’s initial phase 1/2 clinical trial, which began in May.

“We want not only to protect during this immediate pandemic, but also to prepare for what we like to call the nasty variant of the future if one comes along,” Pfizer Senior Vice President William Gruber said recently.

It’s also worth noting that Pfizer has been in discussions with regulators about developing a tailor-made vaccine to combat new variants of COVID-19 and, in particular, the South African strain. The hope is that modified mRNA vaccines can gain rapid regulatory approval, similar to how there are new flu vaccines each year based on new strains.

The company said the following through a press release this week:

Separately, in order to be prepared for any potential strain changes in the future, Pfizer and BioNTech are in discussions with regulatory authorities, including the US Food and Drug Administration (FDA) and the European Agency for Medicines, with respect to a clinical study that allows registration to evaluate a variant-specific vaccine that has a modified mRNA sequence.

This study would use a new Pfizer-BioNTech vaccine construct based on the B.1.351 lineage, first identified in South Africa. This could position Companies to update the current vaccine quickly if the need arises to protect against COVID-19 from circulating strains. Consistent with the updated guidance issued by the FDA regarding the emergency use of vaccines to prevent COVID-19, which provides recommendations for evaluating a modified vaccine to address variants, the companies hope to continue the validation of future modified mRNA vaccines with a similar regulatory pathway. to what is currently in effect for flu vaccines.

Meanwhile, there is a strong possibility that Johnson & Johnson’s one-dose COVID-19 vaccine will arrive early next month. The J&J vaccine was shown in clinical trials to be 85% effective in preventing severe COVID episodes and 66% effective when moderate cases are taken into account.

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A lifelong Mac user and Apple enthusiast, Yoni Heisler has written about Apple and the technology industry in general for over 6 years. His writing has appeared on Edible Apple, Network World, MacLife, Macworld UK, and most recently, TUAW. When not writing and analyzing the latest happenings with Apple, Yoni enjoys watching improv shows in Chicago, playing soccer, and cultivating new addictions to television shows; the most recent examples are The Walking Dead and Broad City.

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