South African coronovirus mutations can infect many times, causing vaccine obstruction.


A mutant strain of the novel coronavirus discovered in South Africa appears to be able to remove antibodies from individuals who had previously recovered from COVID-19 – if the new strain became widespread, we would have infected more people multiple times. Can see

A group of South African scientists made the discovery in a research paper published earlier this week by the National Institute of Communicable Diseases of South Africa. In it, the researchers described how they studied blood samples from a small group of people who had developed COVID-19, but eventually recovered. When the human body recovers from a disease, it produces a protein known as an antibody to identify and eventually protect itself from bacteria or viruses in the future that caused it to become ill. (These disease-causing microorganisms are known as pathogens.) This means that people who were ill with COVID-19 must have antibodies that identify the pathogen that causes it and the event Neutralizes that they are reinforced.

Instead, according to the paper’s authors, protecting antibodies in half of the blood samples of the patients they tested did not necessarily protect against the 501Y.V2 strain of the novel coronovirus, which last month South Africa Was identified in While this was a small study and more research needs to be done, preliminary results are not auspicious.

This can not only interfere with the human population’s ability to develop natural immunity, but it can also hinder the efficacy of Pfizer and Modern vaccines. Both companies are distributing mRNA vaccines, which are different from traditional vaccines that train the immune system to develop antibodies against pathogens by injecting weak or dead versions of disease-causing agents into the body. mRNA vaccines, in contrast, inject a synthetic single-stranded molecule of RNA that infects our own cells and makes them proteins that “spike” on the outer part of the coronovirus. The presence of this protein in the body is recognized as an intruder, and the immune system learns to identify the coronovirus as an enemy and protect against it.

In the case of COVID-19 vaccines, both train the body to recognize a protein on the SARS-CoV-2 virus known as the spike. The spike is the protein that helps the virus to enter human cells and resembles small pins that exit the virus shells, such as the spike that urin around the ocean. Unfortunately, South African mutations alter a lot of protein, meaning that it may affect the efficacy of the vaccine.

South African tension is not the only concern. There is a new strain in Brazil that scientists argue “changes occur even at key positions” in a way that may affect the effectiveness of antibodies against the disease. Then known as B117 in the United Kingdom, although not fatal compared to previous strains, is more contagious.

UCLA’s Postdoctoral Research Scholar Drs. Dylan Morris told the British Stretch earlier this month, “I think transmissible is definitely the go-to word because we uncover what we know and what we don’t know.” “Even if the severity of the disease has not increased or even if it has decreased by a small amount, it is a very scary thing at this point in the ‘more communicable’ epidemic, because of the rapid spread and There may be rapid spread growth. “

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