Potential 2 new coronovirus variants identified in Ohio in the US: Researcher


Ohio researchers announced Wednesday that they had identified two coronovirus variants that likely originated in the United States.

According to the Ohio State Wexner Medical Center, where researchers first identified the variants, “one of the new strains was identified in a single patient in the state,” so that researchers would not know the prevalence of stress in the population.

This new version “has a mutation similar to the UK strain, but it originated in a strain of the virus already present in the United States,” officials said.

Additionally, researchers also found what was described as a “strain developed with three new mutations” that have become “the dominant virus in Columbus over a three-week period between December 2020 and late January”.

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“The new Columbus strain has the same genetic backbone as previously studied cases, but these three mutations represent an important development,” Dr. The statement, said Dan Jones, vice president of molecular pathology and division of lead study author. “We know that this change did not come from the UK or South African branches of the virus.”

He stated that the Columbus version is named COH.20G / 501Y.

The findings were published as pre-print server biorexive and have not yet been peer reviewed.

Researchers at the medical center identified new strains by sequencing the genome of the SARS-CoV-2 virus, which they have been doing since the beginning of the epidemic, in an effort to monitor the “evolution of the virus.” .

“Like the UK strain, mutations found in both viruses affect spikes that span the surface of SRS-Cove-2. Spikes enable the virus to attach to and enter human cells. Like the UK strain, Changes in the Columbus strain. According to university researchers, there is a possibility of making the virus more contagious, making it easier for the virus to be transmitted from one person to another.

Experts expressed concern that the mutations may affect the efficacy of existing COVID-19 vaccines and therapeutics. “We have no data to believe that these mutations will have any effect on the effectiveness of the vaccines now in use,” said co-author Peter Ohler in the study and Peter Moeller, vice president of the Ohio State Wexner Medical Center. Dean for Research at the College of Medicine in a statement.

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“It is important that we do not move beyond this new version until we obtain additional data,” Mohler continued. “We need to understand the effects of mutations on the transmission of viruses, the prevalence of stress in populations and whether it has a more significant impact on human health.”

Monitoring the development of the virus will be important to understand how mutations affect and how doctors treat the virus, he said.

“Viruses naturally mutate and develop over time, but the changes observed in the last two months are more prominent than in the first months of the epidemic,” Jones said.

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