Pfizer Covid Vaccine Produces ‘Robust’ Antibody Response After First Dose, New Study Shows

A new study looking at the effect of the Pfizer / BioNTech coronavirus vaccine found that almost all recipients generated a “robust” immune response after just one dose.

Research from the Universities of Sheffield and Oxford analyzed the immune response in 237 healthcare workers and found that the Pfizer vaccine generated antibody and T-cell responses that would help fight a Covid-19 infection in 99 percent of people. .

It also increased the immune response in those who had been previously infected and already had some natural immunity.

After a second dose of the vaccine, protection was strongest in all groups.

The findings support the UK government’s controversial decision to delay the second dose of the Pfizer vaccine for up to 12 weeks, in order to vaccinate more people with the first doses.

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There had been concern among NHS staff working on the frontline that they were at higher risk by delaying the second dose, but this study seems to show that this would not be the case. While the study looked at the youngest working-age healthcare workers, it did not include older age groups who may have poorer immune responses to vaccines.

Dr Thushan de Silva, University of Sheffield, said: “Our study is one of the largest and most comprehensive accounts of the immune response to a dose of the Pfizer / BioNTech vaccine comparing previously infected and non-infected individuals.

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