Pfizer COVID-19 Vaccine Reduces Transmission After 1 Dose, Study Finds


A single dose of Pfizer and BioNtech’s COVID-19 vaccine could significantly reduce the risk of virus transmission, according to a UK study.

The researchers analyzed the results of thousands of COVID-19 tests that are carried out each week as part of evaluations of health personnel at hospitals in Cambridge, England.

Mike Weekes, an infectious disease specialist at the University of Cambridge Department of Medicine, who co-led the study, said: “This is great news: the Pfizer vaccine not only provides protection against the SARS-CoV-2 disease, but It also helps prevent infection, which reduces the chance of the virus spreading to other people.

“But we must remember that the vaccine does not provide complete protection for everyone.”

The study also found that a single dose of the injection reduces the number of asymptomatic infections.

“Our findings show a dramatic reduction in the rate of positive screenings among asymptomatic healthcare workers after a single dose of the Pfizer-BioNTech vaccine,” said Nick Jones, infectious disease specialist at Cambridge University Hospital. , another co-director of the study. .

After separating the test results of unvaccinated and vaccinated personnel, Jones’s team found that 0.80% of the tests of unvaccinated healthcare workers were positive.

This compared to 0.37% of staff tests less than 12 days after vaccination, when the protective effect of the vaccine is not yet fully established, and 0.20% of staff tests at 12 days or more after vaccination.

The study and its results have yet to be independently peer-reviewed by other scientists, but were published online on Friday.

This suggests a four-fold decrease in the risk of asymptomatic COVID-19 infection among healthcare workers who have been vaccinated for more than 12 days, and a 75% protection, Weekes said.

The level of asymptomatic infection was also cut in half in those vaccinated for less than 12 days, he said.

Britain has been implementing vaccines with the Pfizer COVID-19 injection and one from AstraZeneca since the end of December 2020. The United States is using the Pfizer-BioNTech injection and a vaccine from Moderna Inc. in its vaccination program.

Key real-world data released Wednesday from Israel, which has made one of the world’s fastest launches of Pfizer’s COVID-19 vaccine, showed that two doses of Pfizer’s injection reduced symptomatic cases of COVID-19 in 94% in all age groups, and serious illnesses in almost the same number.

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