Peanut allergy vaccine can “turn off” allergic reactions in mice, scientists say

ANN ARBOR, Mich. –

Scientists are investigating an experimental vaccine that seems to "turn off" a peanut allergy in mice, according to a new study.

Scientists from Mary H. Weiser Food Allergy The University of Michigan center investigated the effects of a nasal spray that was given to laboratory mice three times over the course of so many months.

The researchers said that the vaccine, which has been developing for almost two decades, altered immunity cells in mice with allergies responded to the presence of peanuts, which led to "significant reductions in allergic hypersensitivity."

"By redirecting immune responses, our vaccine not only suppresses the response but prevents the activation of cells that would initiate allergic reactions," the study's lead author, Dr. Jessica O & # 39; Konek, said in a statement. of the press

The vaccine was tested up to two weeks after the final dose was administered.

O & # 39; Konek and other authors of the study say that they will continue their research investigating the physiological mechanisms that suppress food allergies. They also hope to determine how to make the vaccine last longer and potentially carry out a clinical trial to test the vaccine in humans.

The research is published in the Journal of Allergy and Clinical Immunology.


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