PARALYZED mice have stepped up thanks to break through gene therapy, creating a ray of hope for millions of paralyzed humans.
German scientists have demonstrated how they were able to repair the damaged spinal cord of mice by injecting something called a designer protein.
Once injected into the brain, paralyzed rodents who could not use their hind legs were moving again in two to three weeks.
The experiment was performed by researchers at the Ruhr University Bochum in Germany.
They developed a protein called “hyper-interleukin-6” that can stimulate regeneration of nerve cells that have been damaged.
It was genetically engineered because this type of protein does not occur naturally.
Scientists have also genetically created a virus that can hatch damaged cells inside mice.
Once this virus was injected and shared the information it carried, the spinal cord cells inside the mice were able to make proteins themselves.
This meant that they could regenerate the veins that send signals from the brain to the spinal cord.
Lead researcher Dietmar Fisher told Reuters, “The special thing about our study is that the protein is used not only to stimulate the nerve cells that produce it themselves, but also further (to the brain) Through) is done.
“In this way, with relatively small interference, we stimulate a very large number of nerves to regenerate and this is ultimately the reason why mice can move again.”
The researchers were working with mice that had just been paralyzed.
They are now investigating whether their protein still has a positive effect on mice who have been paralyzed for weeks.
This will determine whether the treatment is ready for human trials.
Researchers are working optimally to administer new proteins.
It would be scientifically ground to apply such treatment to humans.
However, first it will need to be tested on mammals such as pigs and dogs.
This is why researchers have emphasized that it can occur three years before treatment on people.
What is paralysis
Paralysis is the loss of action in an organ or part of the body.
Very often due to damage to the spinal cord.
This can occur when there is damage to parts of nerve cells called axons.
This can be caused by a traumatic accident such as a car accident or a bad fall.
The axon is the part of nerve cells that are responsible for sending signals from the brain to other parts of the body such as muscles and skin.
When they are damaged, communication may stop, leaving the patient unable to move or feel in the affected area.
There is currently no cure for paralysis.
However, there have been occasions when some or all of muscle control has returned after treatment for the cause of the injury.
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