Opioids may increase the risk of non-union fracture



The chronic use of certain medications such as opioids, a pain relief can be an important and substantial risk factor for the lack of consolidation of the fracture.

Lack of consolidation is a serious complication of a fracture and can occur when the fracture moves too much or a poor blood supply or becomes infected.

Patients who smoke have a higher incidence of non-union. A study conducted by researchers at Louisiana State University suggests that patients who have not received opioids receive an opiate prescription for post-operative pain control at hospital discharge after major surgery. However, they report that there is no evidence that opioids are more effective than non-opioids for acute pain in the extremities.

"The chronic use of opioids doubled the risk of pseudoarthrosis among all patients, and this effect was fairly constant at all ages and both bades," said Dr. Zura, a researcher.

The investigators reported that opioids in Schedule II, as a group, create a greater risk of non-union than non-opioid badgesics. They also suggested that the chronic use of certain medications can be a significant and substantial risk factor for the failure to consolidate the fracture.

Patients who have not received opioids receive an opiate prescription for post-operative pain control at hospital discharge after major surgery. However, there is no evidence that opioids are more effective than non-opioids for acute pain in the extremities.

The study concluded that there is an inherent risk in the use of most opioid badgesics and emphasizes the importance of non-opioid multimodal badgesic techniques in fracture.

The findings are published in the Journal of Injury. (ANI)

This is published without editing from the ANI feed.

Published: June 17, 2018 5:50 pm


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