One-time screening for COVID-19 misses many infections, researchers warn


Research Trike Park – As the number of COVID-19 pandemic victims increases, so too does the number of deaths, researchers warn that many methods of screening are currently missing multiple infections. Measures to fight COVID-19 are therefore very important.

“One-time screening in apparently healthy people miss those infected. The authors team is unsure whether combined screening, repeated symptom assessment, or rapid laboratory testing are useful, ”says Rescher in a study for which a researcher at RTI RTI International is the lead author.

20–100% of people affected by COVID-19, RTI can miss this approach anywhere.

“As more people become infected, screening will identify more cases. However, because screening may miss people who are infected, public health measures such as face covering, physical disturbances, and quarantine are very important for those who are healthy, “the study warned.”

There is another side effect, the study concludes: screening “may also increase the risk of identifying false positive cases, leading to unnecessary isolation.”

“Our research suggests that the possibility of missing a person with COVID-19 through screening is very high,” Viswanathan, a Ph.D. And an expert in systemic review methodology who is the director of the RTI-UNC Evidence Based Practice Center.

Meera Viswanathan

To improve detection, Viswanathan cited three “key measures:”

  • Screening methods that are more sensitive and accurate
  • A robust public health structure with a test plan
  • Public procurement – test will not succeed without public approval

“Currently, when someone is displayed negatively, the assumption is that they do not have COVID-19. Because asymptomatic proliferation is so common, we cannot make that assumption, ”said Viswanathan. “If more accurate screening methods are developed in the future, and they are being used as a tool to find COVID-19 cases, they are tested and isolated for positive cases and quarantine for those such as Measures must be followed with infected. ”

Studies published through an alliance with scientists, health care providers and others, known as Cochrane, reviewed the results of 20 studies focusing on the COVID-19 trial. They found the following:

  • All screening strategies (17 studies, 17,574 people), incorrectly identified:

20 out of 100 infected people and 100 are healthy
0 out of 100 healthy people and 38 people are infected

  • Asking about symptoms (13 studies, 16,762 people), incorrectly identified:

Between 40 and 100 out of 100 infected people as health
0 to 34 out of 100 healthy people infected

  • Temperature measurement, about international travel, exposure to known infected people and exposure to known or suspected infected people (6 studies, 14,741 people), incorrectly identified

Between 77 and 100 out of 100 infected people as health
Between 0 and 10 out of 100 healthy people infected

  • Asking about temperature measurement with symptoms (2 studies, 779 people), incorrectly identified:

Between 31 and 88 out of 100 infected people as health
0 to 10 out of 100 healthy people are infected

However, the researchers said they had “insufficient evidence from two small studies on rapid laboratory tests and repeated symptom evaluations to explain how accurate they were in identifying healthy and infected people.”