Vaccinating children against the human papillomavirus before they become sexually active can be highly effective, since according to a study men who are infected with HPV16, a type responsible for most cancers related to the HPV, are 20 times more risk of reinfection after one year.
Researchers from the medical center of the University of Chicago in Illinois, USA. UU They found that men with genital papillomavirus (HPV), the most common sexually transmitted infection, have a higher risk of reinfection with the same type.
This increased risk suggests that the infection does not confer natural immunity against HPV, as is often the case with other viruses. The study's lead author, Sylvia Ranjeva of the University of Chicago, said vaccinating children before exposure to HPV could be a very effective way to reduce the burden of HPV infection. Vaccinating men who have already been infected could also be effective.
The study highlights the importance of vaccination to prevent the spread of HPV in young men before they become sexually active. Vaccination may prevent reinfection in older men who have already contracted the virus.
The team analyzed data on the spread of HPV disease in men, who tracked more than 4,000 unvaccinated men from three cities in Florida, Mexico and Brazil. more than five years between 2005 and 2009.
The high risk of reinfection may be due to autoinoculation, to the spread of infection by repeated contact between different sites in the body or to the reactivation of a latent virus.
The results also show that men who are once infected with HPV16, the type responsible for the majority of HPV-related cancers, have a 20-fold increased risk of reinfection after one year, and 14 times more after two years. The researchers also observed the same effect in men who are sexually active and celibate, suggesting they are not acquiring the virus from another sexual partner.
Ranjeva reported that the best thing that men can do is prevent the initial infection by vaccinating children before sexual contact. However, if the increased risk of reinfection is due to self-inoculation, then another effective strategy may also be to vaccinate previously infected men. The research appears in the journal Proceedings of the National Academy of Sciences.
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