Like all new drugs, vaccines that have been authorized to protect against Kovid-19 come with some safety concerns and side effects. Many people who have received the first two western shots from one Pfizer Inc. and Biotech SE, and from another Modern Inc., has experienced fever, headache and pain at the site of injection. These side effects usually disappear quickly. More worrying is Norway Death of elderly people with severe underlying health conditions after administration of the Pfizer-BioNTech vaccine – possibly associated with those side effects. Some other recipients of various jabs have a severe, but treatable, allergic reaction called anaphylaxis.
1. What is known about deaths?
Twenty-nine were reported in January among some 40,000 people given the Pfizer-BioNTech vaccine in Norway, where officials have prioritized the vaccination of nursing-home residents. Those who died were all in the “75 years +” bracket (the exact age was not given for privacy reasons) and it was estimated to be only weeks or months for patients who were ill. All deaths occurring within a few days of vaccination are carefully evaluated. Are close to vaccination time Not necessarily due to shot: average of According to the Norwegian Medicines Agency, 400 people die each week in nursing homes and long-term care facilities. The agency’s chief physician, Sigurd Hortemo, said he could not rule out that common adverse reactions such as vaccines and nausea could potentially be fatal in patients with serious underlying health problems.
2. Have there been deaths elsewhere?
In Germany, where more than 800,000 people have received two doses of the Pfizer-BioNotech vaccine, the Paul Erlich Institute has investigated at least seven cases of elderly people dying soon after vaccination. In its report, it was stated that the deaths were probably caused by patients’. Underlying diseases including carcinomas, renal insufficiency and Alzheimer’s, not vaccination.
3. What were the reactions in these fatal cases?
Deaths were linked in Norway Fever, nausea and diarrhea – relatively common, short-term effects that some people may experience after almost any vaccination, according to information relayed by the Medical Sciences Administration of Australia. (It is working with the European Medicines Agency, which includes Norway, before deciding whether to approve the drug in Australia.) The vast majority of people do not value the reactions. Millions of doses of the Pfizer-BioNotech vaccine have been administered. With America, Britain and some other countries Abrar Chughtai, a lecturer at the School of Public Health and Community Medicine at the University of New South Wales, has not reported any deaths due to the vaccine.
4. What is known about vaccine risk in older, vulnerable people?
Not a big deal. It is possible that common adverse reactions to vaccines that are not dangerous in fitters may occur in younger patients. The underlying disease growing among the elderly, Steinen Madsen, the medical director of the agency of Norway, told BMJ Medical magazine. The agency said that only people over the age of 85 participated in large clinical trials of the Pfizer-BioNotech vaccine. The average test participant for the two accepted Western vaccines was in their early 50s.
5. What is being done in response to the deaths?
The Norwegian Institute of Public Health has updated its Kovid-19 vaccination guide with more detailed advice on vaccinating the elderly who are moldy. “We are now asking doctors to continue vaccinating, but to do additional evaluation of very ill people whose underlying condition may aggravate it,” Madsen said. The assessment involves discussing the risks and benefits of vaccination for patients and their families to decide whether vaccination is prudent. Separately, the Nordic neighboring Finland has recommended against the systematic vaccination of terminally ill patients whose active treatment (in other words, they are being paved) has been stopped. The reason is that common side effects such as temporary fever can weaken their condition.
6. Have there been other serious reactions?
The body fights off foreign invaders through a variety of mechanisms, including creating protective proteins called antibodies, releasing toxins that kill germs and marshalling parental cells to kill them. In any conflict, sometimes an attempt to repel an infection can be damaging to itself. In rare cases, it can cause inflammatory inflammation and swelling of tissues in a severe allergic reaction. Anaphylaxis. As much as 5% of the US population has had such a reaction to various substances. It can be fatal, for example, the person’s airway is closed, although deaths occur. rare. Allergic to Insect stings and foods can provoke it, although drug reactions are The most common cause of anaphylaxis fatal in the US and UK
7. Where are the trigger cases of Kovid-19TK?
As of 1 January 6 Report by the American Center for Disease Control and Prevention, 21 cases of anaphylaxis involving Pfizer-BioNTech vaccine were confirmed in the country on 23 December. Of those, 17 had a documented history of allergy, and seven had a history of anaphylosis. 1 December 19 The CDC’s presentation referred to two cases involving the same vaccine in the UK, and later in the month, in Israel, a person suffered anaphylactic shock an hour after receiving it, According to the Jerusalem Post. He said he had earlier reactions to penicillin, the paper reported. CDC officials say they have also seen reactions in the recipients of Modern Shot and are compiling data on them.
8. Is anaphylaxis first associated with vaccines?
Yes. Such reactions occur at about 1.3 million per dose of the flu vaccine. They have been observed at rates of 12 to 25 per million doses with other vaccines, although studies were small. For the Pfizer-BioNTech Covid vaccine, according to the CDC, the December 23 rate is 11.1 per million doses, which is very low. The agency said the risk around the vaccine is less than the risk of a serious case of Kovid-19.
9. How long does the risk of allergic reaction last?
Usually not for long. Drug development specialist and Associate Vice Chancellor Michael Kinch said that anaphylactic reactions typically occur within hours of exposure to a specific substance. Washington University in St. Louis. According to the CDC, in the US so far, the time interval ranged from two to 150 minutes, while the average was 13 minutes.
10. What is being done about him?
UK And America has advised people who are allergic to any ingredient of the Kovid vaccine, do not get it. Anaphylaxis can be quickly countered with an adrenalin injector such as antihistamine in tandem Mylan NV’s Epi-Pen that slows or inhibits immune responses, and vaccine health workers keep such items ready. These treatments do not rule out the beneficial effects of vaccines. In the US, health workers are watching everyone who receives a vaccine for at least 15 minutes to get a vaccine indicated for a reaction; People with a worrying history of allergic reaction are monitored for twice as long. People who have reacted to the first dose of the vaccine should not receive a second medication CDC.
11. Do we know what reactions happen in shots?
It is not clear. There are two main candidates Polyethylene glycol – a chemical found in many foods, cosmetics and medicines – and Lipid nanoparticles, which encapsulate messenger RNA, a genetic component in the vaccine, according to Eric Topol, a clinical trial expert and director Scripps Research Translational Institute. Having polyethylene glycol A handful have previously been associated with anaphylaxis cases. Topol said that once a cause is reduced, it may be possible to make Kovid vaccines safer.
– assisted by Lars Erik Taraldsson, and Kati Poojanpalo