Singleton, 51, was on the premises Wednesday when he had the stroke, the family said in a brief statement that did not include details.
Hollywood celebrities went to social networks to send Singleton good wishes.
Actor Omar Epps, who appeared in the movie "Higher Learning" directed by Singleton, tweeted: "Wishing the director John Singleton a quick recovery from his stroke, one occasion, perhaps, for the rest of us to be surprised that the human physiology work at all. "
Rapper Snoop Dogg posted an image of himself and Singleton on Instagram saying, "Pray 4 brother."
Film director Guillermo del Toro, a two-time Academy Award winner, wrote on Twitter: "Good for you, John Singleton, such a generous spirit."
Singleton was nominated for best director and best screenplay for "Boys n the Hood", which was released in 1991.
Film critic Roger Ebert praised the film as a "human drama of rare power."
"Singleton is a director who brings together two attributes that are not always found in the same film: he has a theme and has a style," Ebert wrote. "The film is not only important, it is also a joy to watch, because your camera is very safe and wins such natural performances from its actors."
Singleton was the first African-American nominated for best director.
His most recent work includes the FX show "Snowfall", about the crack boom in Los Angeles. Singleton is one of the creators and executive producers of the show. According to the Internet Movie database, Singleton directed three episodes.