Immunity of coronovirus lingers for months, study found


While the report may find a similar report out of Britain this week to be misleading and contradictory, it really is not. People’s bodies produce an army of immune compounds in response to an infection and some become heavy at first, dying quickly, while others build more slowly.

The new report on Wednesday shows 90% of people who recover from Kovid-19 infection have a stable antibody response.

“While some reports state that antibodies to this virus move quickly, we have found the exact opposite – more than 90% of people who were mildly or moderately ill were sufficient to neutralize the virus. An antibodies produce the reaction, and the reaction persists for several months, ‚ÄĚProfessor Florian Kramer of the vaccine at the Econ School of Medicine in Mount Sinai, who led the study team, said in a statement.

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The team observed antibody responses of more than 30,000 people who tested positive for Kovid-19 at Mount Sinai’s health system between March and October. They represent their antibody responses as low, medium, or high. The virus had high levels of antibodies for the spike protein, or more than 90% of the medium for titers – the structure that holds it to infected cells.

He then closely studied 121 patients, who first developed plasma and then donated their plasma five months later to cure symptoms and again five months later.

He observed a drop in some antibodies. But others persisted, he reported in Science magazine.
New report suggests coronovirus immunity may persist for months

“The serum antibody titer we measured in individuals was initially produced to come together with plasmablasts, cells that act as the first response to an invading virus, and antibodies whose initial bouts soon produce potency, “Dr. Said Ania Kazanberg, director of clinical. Antibody Testing at Mount Sinai Hospital.

“The sustained antibody levels that we later observed are produced by long-lived plasma cells in the bone marrow. This is similar to what we see in other viruses and chances are they are here to stay. We Will continue to follow the group. To see if these levels are stable as we are skeptical and hope they will. “

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Antibodies are not only the immune system mustard protection against infection, but they are an important first line of defense.

The team wrote, “While this may not provide conclusive evidence that these antibody responses protect from recombination, we believe that it is likely that they will reduce the ratio of reinforcement.”

Kovid-19 has only been around for less than a year, so scientists are still learning about it. The stories of people being infected more than once are mostly tales, and few and far between.

There is a clear concern about this. It would be far better to get rid of the epidemic if people develop permanent immunity to the virus after infection. And, of course, immunity will be important for a vaccine to function well.

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It occurs with other viruses. Measles is an example. A bout of measles usually leaves someone immune to life – an effect known as sterilizing immunity. The same was true for smallpox, before the virus was wiped out by a global vaccination campaign in the 1970s. And proper vaccination against measles and smallpox completely prevents infection.

But respiratory viruses such as influenza are complicated. People can catch the flu frequently and flu vaccines usually provide partial protection against infection and critical illness. The reason for this is the tendency of the flu to mutate.

Coronaviruses begin to fall in between. They can cause the common cold, but because they are not usually fatal, they are not well studied. There was little interest in coronavirus until Kovid-19’s deadly cousin Sars came along.

Nevertheless, there is evidence that people can and do develop some immunity to coronavir.

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“We know from work with normal human coronaviruses that antibodies are neutralized, and that these antibodies can last for years and provide protection from re-infection or tuberculosis, even if the individual is reinforced,” Wazenberg And colleagues wrote.

“It is still unclear how long infection with SARS-CoV-2 in humans protects from regeneration and for how long.”

The next important step, he said, would be to establish what is known as the correlation of security. These are compounds that can be measured in the blood that will tell doctors if there is any immunity – so that it won’t be necessary to wait and see if they become infected once again, or to get a vaccine. after.

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