How coronovirus nearly killed a healthy woman with “no common symptoms”


London – Rebecca Wrixon knew that working as a nanny for a pair of doctors could give her exposure to coronovirus, but as a healthy 44-year-old child, she was more about catching COVID-19 Does not worry It was already clear, in early April, that the disease struck the elderly and those in whom the underlying conditions were difficult, but it was not too much of a threat to their healthy family.

Rebecca Vickron is seen at University Hospital Southampton for the treatment of severe inflammation of the brain caused by the Kobe-19 infection.

Courtesy of Rebecca Wrixon


Then in the morning, just a day after Easter, the Wexen numb woke up.

She never had a cough or fever, never lost her sense of taste or smell, and it would take doctors several days to diagnose COVID-19 – and figure out how to stop her body’s reaction. Insidious disease caused her body to attack silently, inflating her brain, paralyzing half of her body, being unable to see or speak, and nearly killing her in the process.

Researchers in the UK believe that COVID-19 can kill many more people with similar neurological symptoms than are commonly thought – including young patients and people like Vexen who are the most well-known symptoms of the disease ever Do not experience

The fear is not only that these symptoms can be dangerous on their own, but that they can apply ginger, and no one is aware yet.

“No common symptoms”

Vixen’s 11-year-old daughter was in bed with a fever for about a day in early April, when Waxton herself experienced chest pain and mild rash, but she never suspected that it was a coronovirus.

“I didn’t have any common symptoms like they tell you to look outside. I just didn’t feel well, and just had itching around my chest and a pain from my chest, but no cough. No No problem breathing or anything like that., “And then it all cleared up, he told CBS News from his home on the south coast of England.

“It wasn’t until the Tuesday after the Easter holiday that I got up and my hand was numb.”

When her husband came down and struggled to operate the TV remote, she told him that she could not feel his hands or feet. Both Wrixon and her husband thought the same thing.

Her husband asks her to tell her daughter’s birthday and a couple other basic facts.

“I couldn’t answer. Didn’t have a clue,” recalled Wexen. “So that’s when we were like, ‘I’m a jerk.”

He called an ambulance and was taken to the emergency room.

“Thought I’m going to die.”

“It looked like he had taken a stroke,” consultant neurologist Drs. Said Ashwin Pinto, who ended up wrestling with the case of Waxton for nearly three weeks. “Soon after actually seeing Rebecca, she was really starting to struggle with her speech.”

Coronavirus, he said, “was not really on the radar.”

But the test quickly confirmed there was not a stroke. Over the next few days, as Wrixon’s condition worsened and the magnitude of the epidemic began to be recorded across Europe, he was tested for COVID-19 as a course.

“I didn’t think, especially, that it was going to be positive,” Pinto said.

The result shocked him. However, despite the positive larynx swab test, the virus had nothing in its blood or spinal fluid to suggest that the virus was directly attacking its central nervous system. But some MRI scans caused severe swelling in more than half of his brain.

f1-large.jpg
MRI images show a scan of Rebecca Vickron’s brain on the day she was hospitalized (A), six days after admission (B) and 17 days after admission (C), with swelling in a light shadow.

American Academy of Neurology / University Hospital Southampton


At this point, Wrixon could not move half of her body. She could not see clearly and could not communicate with her doctors or her husband.

As the leading neurologists understood what was wrong, Varico’s husband could not find any guarantee. His daughter asks him to promise that mother is going to come back home. He said that the doctors are trying their best, but he cannot promise anything.

“I felt like I was going to die. I really thought, ‘No, you’re not coming out,” Waxen told CBS News.

wrixon-hospital.jpg
Rebecca Wrixon lay in her bed at the University Hospital of Southampton in England in early April 2020, just before doctors began giving her plasma exchange treatment. At this point there was an inflammation in his brain due to COVID-19 infection, due to which Vetrixen was unable to move half of his body, see or speak clearly.

Courtesy of Rebecca Wrixon


Dr. Pinto knew of just one or two cases outside Britain that looked similar, at least on paper. He read a study in Detroit about a patient whose autoimmune response to COVID-19 infection caused a similar, severe inflammation of the brain, so he decided to take a gamble and not for viral infections, Vaccine treated. Immune systems run amok.

Once the COVID-19 infection had passed and he tested negative for the virus, Pinto started giving high-dose steroids and blood plasma exchange to Wrixon. The exchange is sufficient to remove the patient’s plasma – the part of the blood that gives antibodies to fight infection – and is replaced by donors with a protein that the immune system does not outweigh. To prevent body reaction and reduce inflammation.

It worked.

“As soon as the plasma exchange started, the next day I woke up and I moved my first finger,” Wexon said. After five days of treatment, she again stood up. “I was moving around. In fact, plasma exchange works a miracle.”

She went home after more than two harrowing weeks in the hospital, and has since recovered almost completely. Three months later, Wexton still has pain and numbness in his hand, and sometimes he struggles to get his words out.

Concerning a “growth”

Along with the overall prevalence of neurological symptoms in COVID-19 patients, how long those effects may last, Dr. Pinto continues to worry, and he is not alone.

Two recent British studies make it clear that while it is better understood than before, new coronoviruses are still guarding secrets.

A study published on 8 July in the journal Neurology Brain Of the 43 patients with confirmed or suspected COVID-19 infection, 12 suffered central nervous system inflammation including the brain. Of those 12, one made a full recovery, 10 made a partial recovery, and one died.


COVID-19 blood clotting secret

5:28

COVID-19 infection is “associated with a broad spectrum of neurological syndromes,” the study authors concluded. He called it “striking” to note, in particular, the “high incidence of acute diffuse encephalomyelitis” (ADEM is widespread inflammation in the brain and spinal cord) in patients.

The study at the National Hospital for Neurology and Neurosurgery at University College London also noted that, as Vixen found, severe inflammation, “respiratory COVID-19 was not related to the severity of the disease.”

According to University College London, the neurologists behind the research said they would usually treat one adult patient per month with ADEM, “but this increased to at least one week during the study period. [which coincided with the height of the COVID-19 outbreak in London], Which the researchers say is related to the increase. “

A big study published in the Lancet, Which includes data from UCL research, looked more broadly at the prevalence of neurological symptoms in COVID-19 patients. It “identifies a large proportion of cases of acute changes in mental status, including encephalopathy and encephalitis, and psychiatric diagnoses such as primary psychiatric syndromic diagnosis.”

The study found that in 125 coronovirus patients, 62% presented with a “cerebrovascular event” [stroke]Of which 57 (74%) had an ischemic stroke, nine (12%) an intracarbral bleeding, and one (1%) CNS vasculitis. [inflammation of blood vessels in brain or spine]. “

It is understood that COVID-19 patients, young and old, but especially older people, often experience stroke, but the researchers were surprised by the prevalence of psychiatric symptoms in younger patients who (again, e.g. Wrixon) are not victims of stroke. In the graph below, “cerebrovascular” indicates patients in the study who experienced stroke, while “neuropsychiatric” refers to patients with other cognitive and physical symptoms, and it shows a clear shift with aging.

Lancet-covid study-centuries chart.jpg
A graph from a study published in The Lancet shows the proportion of COVID-19 patients among a study group who experienced stroke (“cerebrovascular”) compared to those who experienced other cognitive and physical “neuropsychiatric” symptoms broken by age group. ) Experienced.

the Lancet


Any disease affecting the central nervous system can have long-term health implications, as millions of stroke survivors may suffer injuries. Viruses, ranging from the common flu to the “Spanish flu” that caused global havoc between 1918 and 1920, often leave their mark on survivors of brain damage.

Dr. Pinto said that after the 1918 epidemic, doctors saw an increase in cases of a neurological disease called encephalitis smoothie, many of which were suspected to have delayed the virus’s response.

“If you follow the films, that’s the film, ‘Awakenings’, with Robert De Niro – it’s all about the patients who have recovered from the 1918-1920 epidemic,” he said. “We therefore know that viruses have been associated with prolonged brain exposure.”


Similarities between Spanish flu and COVID-19

2:31

“Don’t we really, really with coronovirus know what that would look like” Pinto said. “We’re going to see it playing in real time.”

“It’s not influenza”

“There are a lot of people out there who are still thinking it’s the flu, and in fairness, that’s what I was thinking before I got sick,” Wrixon told CBS News. “But now? Yes, there is no way I want anyone to pass by me.”

“Staying in the hospital on your own and no family or friends are allowed to see you or see you or talk to you, yes, I wouldn’t want anyone to go through that.”

“This is not influenza,” Dr. Pinto emphasized. “We have small influenza outbreaks in every country in the world, seasonal in winter, … we have documents No We saw the extent of the terrible complications that occur with this virus. ”


Trump’s coronovirus briefing returns

4:57

Wrixon said that it was difficult now that pictures of people gathering in large groups could often see their photos without wearing masks.

“It’s ridiculous, in fact, people aren’t looking at it more seriously.”

Click To read here Full academic study on Wrixon’s case.

.