For Covid-19 Survivors, A Single Injection May Be Enough, Preliminary Studies Show


Covid-19 survivors who have received a first dose of the Covid-19 vaccine are generating immune responses that could make a second injection unnecessary, potentially freeing up the limited supply of vaccines for more people, several new research articles suggest.

The research, while preliminary, found that previously infected people generated protection against the disease rapidly and at dramatically higher levels after a first injection of the current two-shot regimens compared to people who were vaccinated but had not been ill. .

“Everyone should get vaccinated. Not everyone needs two injections, ”said Viviana Simon, a professor of microbiology at the Icahn New York School of Medicine at Mount Sinai and the author of one study. “As long as we can’t deliver as much vaccine to everyone who wants it, I think that’s an important consideration.”

The research, which has been published on prepress servers but has not been peer-reviewed or published in a scientific journal, comes as other findings in the two-injection regimen for healthy members of the general population highlight immunological benefits after injection. first injection. On Friday, researchers in Israel reported that a single injection of the vaccine from Pfizer Inc. and BioNTech SE is 85% effective in preventing symptomatic illness 15 to 28 days after administration.

Late-stage clinical trials of two-dose vaccines conducted by Pfizer and BioNTech, as well as Moderna Inc., have shown that their injections are safe and highly protective against Covid-19 when given in two doses several weeks apart. However, the Pfizer trial excluded people with symptomatic Covid-19, and Moderna excluded people with a previously known infection, leading the researchers to see how immune systems responded in previously ill people.

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