Flu vaccine prevents hospitalization in kids

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influenza
Electron microscopy of influenza virus. Credit: CDC

Children vaccinated in opposition to influenza are considerably much less prone to expertise severe problems from the virus that would land them in hospital, new badysis from Public Health Ontario (PHO) and the Institute for Clinical Evaluative Sciences (ICES) has discovered.

Published within the Nov. 17 difficulty of PLOS ONE, the examine discovered that younger kids who have been totally vaccinated in opposition to influenza noticed their danger of hospitalization on account of influenza an infection drop by 60 per cent general. Even for youngsters partially vaccinated in opposition to influenza (i.e., those that obtained one dose of influenza vaccine throughout their first influenza season), danger of hospitalization on account of influenza dropped by 39 per cent.

“Influenza can cause serious illness, especially in young children, but there hasn’t been a lot of research that has examined the magnitude of the influenza vaccine’s effectiveness at preventing kids from getting really sick and being hospitalized,” says Dr. Jeff Kwong, a scientist in Applied Immunization Research and Evaluation at PHO and a senior scientist at ICES. Dr. Kwong is the senior creator of the badysis paper.

“This research paper helps fill that gap by showing how effective the influenza vaccine can be at protecting young kids against serious complications from influenza infections,” provides Dr. Kwong.

The researchers examined practically 10,000 Ontario hospital data of youngsters aged six months to beneath 5 years the place a respiratory specimen was collected and examined for influenza; 12.eight per cent confirmed lab-confirmed influenza. The scientists included 4 influenza seasons – 2010-11 to 2013-14 – and broke the information down to match kids who have been totally vaccinated, partially vaccinated and those that did not get the vaccine. They additionally in contrast variations by age group and the circulating influenza strains every season.

Overall, totally vaccinated kids aged two- to four-years-old noticed their danger of hospitalization on account of influenza drop by 67 per cent whereas these aged six to 23 months noticed their danger drop by 48 per cent.

“These results show that flu vaccines are effective at preventing influenza hospitalizations in young kids, and this extended to those who received their vaccination in two consecutive seasons. This contributes to the evidence that this group should be receiving their seasonal vaccine annually to prevent such serious outcomes,” says Sarah Buchan, a PhD candidate on the University of Toronto and the examine’s lead creator.


Explore additional:
Annual influenza vaccination doesn’t stop pure immunity

Journal reference:
PLoS ONE

Provided by:
Public Health Ontario

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