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Experimental dental material kills to prevent plaque



When a cavity is filled, the plate is not desired to grow in the presentation, as it could cause the tooth to decompose again. That's why scientists at the University of Pennsylvania have evaluated a new experimental dental composite material that not only kills plaque-causing bacteria on contact, but also resists daily wear and tear.

First of all, there are and other antibacterial dental composites, which generally work by slowly releasing compounds that kill bacteria. Unfortunately, such compounds can be toxic to the surrounding tissue, in addition to which they can contribute to antibacterial resistance. In addition, its presence within the compound can compromise its mechanical strength.

The new material is made of a resin impregnated with the antibacterial agent imidazolium. That resin is not leachable, which means that the imidazolium is not released from it. Instead, the agent remains in the filling (or other restorative dental work), only killing microbes that actually touch it. The material also "has excellent mechanical properties", easily supporting activities such as biting and chewing.

In laboratory tests, it was discovered that the resin is very effective in preventing the bacterial biofilm (plaque) from growing on its surface. Only a negligible amount grew, and was easily removed using very little cutting force. In contrast, a control sample of a conventional dental compound accumulated much more plaque, which required more than four times as much force to remove.

The study was funded by dental technology firm Dentsply Sirona, and is described in a paper that was recently published in the journal ACS Applied Materials and Interfaces .

Source: University of Pennsylvania

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