Novartis researchers are working to eradicate pressure



They are making false mistakes. Cancer cells get rid of the brain healthy, but they break down their actions and remove the natural defenses of the people 's body. The system does not protect the world.

Novartis drug dealers and world-wide cosmopolitan researchers are looking for ways to proceed further. New cancer treatment vaccines benefit many patients, but there is space for wider access.

Scientists Novartis are investigating a number of ways to protect cancer response, including learning protective cells, acting them, and promoting their response to a protective response. In addition, they're researching defense-protecting maids by looking for clues within a plunger that may help them find out the correct defenses with the correct patient.

Education education

Long-guard cells in the defense system are lifelong students. They can be taught to attack unwanted attackers, including cancer cells. One way in which a Novartis scientist takes his studies to defense education, the use of cellular Chileric cells (CAR-T) is used. This approach trains patients' own defense cells – special cells called T cells that work as soldiers of the immune system – to identify and attack cancer cells. Training involves introducing the T-cells to the cells T is what they have to do to make a sensor that identifies an enemy flag at cancer cells. Here the T-CR cells (shown in green) are known to cancer cells (red) and launched an attack.

Protective action

Like a slick con artist, cancer knows how to make a fool of the immune system think that disease cells have not attacked them. The parts he has had to play their tricks as a normal part of the defense system. They can change defense behavior in many ways, such as by grappling with thick cells or by destroying cells of defense. Novartis researchers are examining a variety of methods to remove these false molecular signals and activate security cells. For example, one mark taken over by tickets is called a “check check”, a set of brakes that usually keep cells protecting from healthy, destructive cells. Corpses chase the check marks to protect the defense system's infantry, the T cells, from attacking cancer cells. Here a guardian has taken a check-check of the brakes and activated T (blue) cells to attack and destroy cancer cells (pink).

An infamous environment

Beautiful, do not? It can show he's looking deceitful. This is a shoe. There is so much more going on in the growth of cancer cells. Researchers understand that the parts of pressure around cancer cells, the food microenvironment, may be as important as considering the cancer cells. Novartis scientists are finding ways to encourage the main microanvironment to ensure more effective protection.

Making protective maids

Why do some patients respond to treatment when other patients do not? It's confidentiality, but Novartis scientists think the information about the box itself may reply to it. For example, spreading a host of cells in a shoe may give you clues about how good a patient could be. To investigate this potential, Novartis scientists have moved into false (AI) predictions to see if computer programs can locate images from images of cancer pathology. As a first step, pathologists Novartis work with startAI tech PathAI to train the AI ​​platform to identify types of cells that are experienced in geometry. Here AI has a thick cell (red), cells protecting (green, yellow), and other cells (black, purple).


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