The new use of breath and urine tests can detect early stage breast cancer, the most commonly diagnosed cancer among women in the world.
Breast cancer biomarkers were accurately detected in a new study by researchers at Ben-Gurion University using two sensors "nasal gas" in respiration and gas chromatography mass spectrometry (GC-MS): a method to analyze substances found in urine.
"Survival of breast cancer is strongly linked to the sensitivity of tumor detection." Co-author of the study, Yehuda Zeiri said in a statement. "Precise methods to detect smaller and older tumors remain a priority (and) our new approach that uses urine samples and exhaled breath, analyzed with commercially available economic processes, is non-invasive, accessible and can be easily implemented in a variety of environments. "
The research, published in the journal Computers in Biology and Medicine, found that the breathing method could accurately detect cancer cells more than 95% of the time with the electronic nose. The low-cost device detected the disease by detecting a unique breathing pattern in women.
Similarly, the urine test proved to be accurate 85% of the time.
The current major method of breast cancer screening using a mammogram may not always detect very small tumors in dense tissue, according to the study. The tests are typically 75% to 85% accuracy, but that number is reduced to 30% to 50% in women with a fuller body. And a dual-energy digital mammogram, a more efficient means of finding small tumors, is expensive and exposes patients to radiation. The only invasive and difficult-to-extract biopsies are the only ones
"We have now shown that economic and commercial electronic noses are sufficient to classify patients with cancer in early stages," Zeiri said. "With more studies, it is also possible to analyze exhaled breath and urine samples to identify other types of cancer, too."
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