Disease severity, gut bacteria tied to immune response; High mental health toll seen in ICU

(Reuters) – The following novel is a roundup of some of the latest scientific studies on coronovirus and an attempt to treat and vaccine for the virus-causing disease COVID-19.

FILE PHOTO: Infrastructure Morphology, as demonstrated by Novel Coronavirus (2019-nCoV) of 2019, is seen in an illustration released by the Centers for Disease Control and Prevention (CDC) on January 29, 2020 in Atlanta, Georgia, USA. Alissa Eckert, MS; Dan Higgins, Mam / CDC / Handouts Through REUTERS.

Severity of gut bacteria COVID-19, tied to immune response

The microbes living in our intestines can affect the severity of COVID-19 and the body’s immune response, and may be responsible for the lethargic symptoms, the researchers reported in the journal Gut on Monday. They found that intestinal microorganisms in COVID-19 patients differed significantly from those in uninfected individuals. “COVID patients lack some of the best bacteria known to regulate our immune system,” Dr. of the Chinese University of Hong Kong. SIV NG said. They stated that the presence of abnormal classification, or “dysbiosis” of gut bacteria persists after the virus has gone away and may play a role in long-lasting symptoms that plague some patients. His team has developed an oral formula of living bacteria known as probiotics and a special capsule to protect organisms until they reach the intestine. “Compared with patients on standard care, our pilot clinical study showed that more COVID patients receiving our microbiome immune formula achieved full symptom resolution,” Ng said, adding that those who received it, The markers for their blood inflammation were significantly reduced, becoming favorable. Bacteria in their feces and they developed antibodies to neutralize the virus. (bit.ly/3q9u1hb)

Epidemic overshadows mental health of ICU workers

Researchers reported in Occupational Medicine on Wednesday that around half of employees working in intensive care units (ICUs) in England have severe anxiety, depression or traumatic stress disorder, with some finding it better. The study was conducted in June and July – before Britain began experiencing its latest growth in hospitals. Among more than 700 healthcare workers in nine ICUs, 45% met the threshold for potential clinical significance for at least one of four serious mental health disorders: severe depression (6%), PTSD (40%), Serious anxiety (11%) or drinking problem (7%). One in eight reported persistent self-harm or suicidal thoughts in the past two weeks. Researchers said mental health among ICU staff caring for critically ill and dying COVID-19 patients not only harms their quality of life, but also impedes their ability to work effectively Is, the researchers said. The findings state the urgent need for mental health services to be immediately accessible to all health workers. (bit.ly/2LN5SOQ; reut.rs/38GlzAn)

Cooling vest helps COVID-19 nurse to bear PPE

A small study suggests that nurses in COVID-19 wards wear cooling vests under their personal protective equipment (PPE). Seventeen nurses wore a light-weight cold vest under their PPE one day, and only PPE the other day. On both days, participants swallowed an electronic capsule that provided continuous readings of body temperature. Researchers made slight improvements in body temperature, but a major improvement in the sensation of getting too hot, the researchers reported in the journal Temperature. Only 18% of nurses reported thermal discomfort at the end of the day and 35% slightly warm thermal sensation. 81% and 94% compared to that day, without vest. “PPE is known to induce heat stress, which increases fatigue and sensory resentment, and according to a study by Thijs Eyesvogels of the Medical Council Center Redboud in the Netherlands, it is known to make effective decisions The Coolover Vestage, created by Dutch company Inutek, is easy to disinfect and reactivate in refrigerators, he said, and can extend work tolerance time and improve the recovery of physicians involved in COVID-19 care. ( bit.ly/2K9sXe5)

COVID-19 risks for black patients include diabetes

Black patients with type 1 diabetes (T1D) who become infected with the new coronovirus are particularly at risk of diabetes known as ketoacidosis, new data show. T1D usually develops in children or young adults and requires daily insulin to survive. Researchers studied 180 patients across the United States with T1D and COVID-19, with 31% being Black and 26% being Hispanic. The researchers reported in The Journal of Clinical Endocrinology and Metabolism that they were nearly four times more likely to develop diabetic ketoacidosis (DKA) than white patients. Hispanics had a slightly higher risk than white patients. Blacks and Hispanics were significantly less likely to use new diabetes technology such as frequent glucose monitoring and insulin pumps, and had significantly worse blood sugar control than white patients. It was suggested that the possibility of high risk was driven by structural and systemic inequality, co-scientist of the nonprofit T1D Exchange in Boston, Dr. Osagie Abecozian told Reuters. Especially during epidemics, healthcare providers are required to screen patients with T1D for socio-economic factors that increase the risk of DKA such as food insecurity, insulin overdose, and access to diabetes supplies , The researchers said. (bit.ly/3hWJZs8)

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Reporting by Nancy Lapid and Megan Brooks; Editing by Bill Burcott


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