Home / Health / Depression is a potential side effect of more than 200 common prescription drugs, scientists warn

Depression is a potential side effect of more than 200 common prescription drugs, scientists warn



One study found that one third of adults in the US UU You may be using prescribed drugs that could cause depression or increase the risk of suicide.

A team of scientists at the University of Illinois at Chicago warned that 200 commonly prescribed drugs carry warnings that depression or suicide are potential side effects.

But patients and doctors may be unaware of this link because medications can treat conditions not related to depression or mental health. These include some analgesics; blood pressure and medication for the heart; hormonal contraceptive pills; Proton-pump inhibitor; and antacids.

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<p class =" canvas-atom canvas -text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm "type =" text "content =" It is believed that the study published in the Journal of the American Medical Association is the first to reveal that polypharmacy, where several drugs are taken at the same time, is associated with an increased risk of depressive symptoms. " data-reactid = "15"> The study published in the Journal of the American Medical Association is believed to be the first to reveal that polypharmacy (in which several medications are taken at the same time) is associated at an increased risk of depressive symptoms.

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = " Scientists warned that one-third of American adults take medications related to depression. Getty Images " data-reactid = "27"> [19659007] Scientists have warned that a third of American adults take medications related to depression. Getty Images

About 15 percent of participants who took three or more of the medications identified in the study reported experiencing depressive symptoms while using them. In contrast, 5 percent of those who did not use the medications and 7 percent of those who took a medication said they had experienced depression. Another 9 percent of those who took two of the medications felt depressed. The team found similar patterns in medications that listed suicide as a potential side effect.

To compile their study, the researchers evaluated data from the National Health and Nutrition Survey, which documented the use of prescription drugs by more than 26,000 adults between 2005 and 2014.

Dr. Dima Qato, assistant professor of pharmacy systems, results and policy at UIC College of Pharmacy, and author of the study, said in a statement: "Many will be surprised to learn that their medications, despite having nothing to do with the mood or anxiety or any other condition normally associated with depression may increase the risk of experiencing depressive symptoms and may lead to a diagnosis of depression.

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" People are not only using more and more these medications alone, but they use them more and more, however , very few of these drugs have warning labels, so until we have public or system level solutions, it is left to p Experts and health professionals must know the risks. "

Professor Andrea Cipriani, associate professor of psychiatry at the University of Oxford, United Kingdom, said the document is "important" but "not alarming" and highlighted two important caveats.

"First, the risk of depression was higher in people who took more types of medication and this may be the result of the interaction of medications, but it may also be because people with chronic diseases take more medications and It is also more likely to have depression This was an observational study, so we can not detract this.

"Secondly, this study analyzed many medications, including antidepressants. For many of the people who reported the depression, this could simply be because the antidepressants in particular did not work for them, or that they were predisposed to expect feelings of depression. It does not necessarily mean that antidepressants caused depression. "

Professor David Baldwin, chairman of the Psychopharmacology Committee of the Royal College of Psychiatrists, said:" The findings emphasize the need for doctors to ask about all prescriptions and medications. of over-the-counter -contact medications when patients have depressive symptoms.

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"If there is a risk of worsening these symptoms, especially when they are taking several medications, then the patient's condition could be improved by a change in their prescription.This could prevent unnecessary antidepressant treatment."

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Dr. Ian Anderson, professor in the division of neuroscience and psychology The University of Manchester experimental study, based in the United Kingdom, did not participate in the study, however, he said Newsweek the findings are potentially important for emitting light in an area of ​​medicine that is not generally considered . "data-reactid =" 41 "> Dr. Ian Anderson, a professor in the division of neuroscience and experimental psychology at the University of Manchester, based in the United Kingdom, did not participate in the study. However, he said Newsweek the findings are potentially important to shed light on an area of ​​medicine that is not generally considered.

More research is needed to find out if those who reported symptoms of depression were diagnosed with clinical depression; if the medication or the participant's depression came first; and if a drug that has an association with depression in its side effects is, to some extent, arbitrary.

"Drug users associated with depression may have had more conditions that in turn are associated with depression," Anderson argued. An analysis of those with only medications associated with depression and without the association would also clarify the results.

As for those affected, their medication could be causing depression, Anderson said the study should not lead anyone to stop medicating, as this should always be discussed with a doctor.

Anderson suggested that anyone whose moods persistently worsened, especially inexplicably, after starting with one or more medications, should discuss this with a doctor. It is possible to try an alternative treatment.

"Interactions between multiple medications is extremely difficult to predict, so it is also worth wondering if all the medications that are taken are necessary, in terms of simplifying medication regimens when possible," he said.

<p class = "canvas-atom canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = " This story has been updated with Professor Ian Anderson's comment "data-reactid =" 47 "> This story has been updated with the comment of Professor Ian Anderson.

This article was originally written by Newsweek

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