Critical patient in France after reinfection with South African variant – tech2.org

Critical patient in France after reinfection with South African variant


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Doctors in France are treating a critically ill patient infected with the South African variant of the coronavirus, four months after he recovered from Covid-19, in what the study authors said was the first case of its kind.

The 58-year-old had a history of asthma and initially tested positive for Covid-19 in September when he presented to medical staff with a fever and shortness of breath.

The symptoms persisted for only a few days and the man tested negative for Covid-19 twice in December 2020.

However, he was admitted to the hospital in January and diagnosed with the South African variant.

The patient’s condition worsened and he is currently in “critical condition” on a ventilator.

“This is, to our knowledge, the first description of reinfection with the South African (variant) that causes severe Covid-19, four months after a first mild infection,” said the authors of a study published this week in the journal Clinical Infectious. Diseases.

More contagious

The 501Y.V2 variant of the coronavirus emerged late last year in South Africa and immediately caused alarm among disease specialists.

It has eight key mutations, one of which affects the spike protein of the virus, making it more efficient at binding to human cells, and therefore more infectious.

Vaccine makers Pfizer / BioNTech and Moderna say their mRNA vaccines retain their effectiveness against South African variants and another that emerged last year in Britain.

However, a study last week showed that the AstraZeneca vaccine was unable to prevent mild and moderate cases of South African variant infection.

“The impact of 501Y.V2 mutations on the effectiveness of vaccines developed from older SARS-CoV-2 strains is still unknown,” said the authors of the reinfection study.

(AFP)

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