COVID-19 disappoints in study Remedisvir; Breast milk transmission is unlikely


(Reuters) – The following novel is a roundup of some of the latest scientific studies on coronovirus and an attempt to treat and vaccine for the virus-causing disease COVID-19.

New questions about Remdesivir COVID-19 efficacy

A new study is raising new questions about the efficacy of Gilead Sciences Inc. (GILD.O) Anti-viral drug remediesvir in COVID-19 patients. Research published Friday at JAMA, a randomized, controlled trial of Remedisvir in 584 randomly ill COVID-19 patients, yielded disappointing results. The study found that the 10-day course of the drug did not show a statistically significant effect on the course of the disease, compared to the standard treatment of 10 days without medication, 11 days after the start of treatment. The five-day remediesavir course made a statistically significant difference, but one so short that researchers are not sure it really matters. Several other gold-standard tests are still underway, but as important questions remain regarding the efficacy of Remedisvir, Erin McCarey and Derek Angus of the University of Pittsburgh wrote in an editorial published with the study. They raised questions about whether some patients receive more benefits from Remedisvir than others, and whether it matters whether patients receive Remedisvir and Steroids together. It is still possible that Remedisvir could improve recovery for the millions of patients hospitalized with COVID-19, he said, but that would be evident before more research is needed. Remdesivir is currently sold under an Emergency Use Authority from the US Food and Drug Administration to treat patients with severe COVID-19. Gilead has filed an application for full FDA approval. (bit.ly/2E59k3T; bit.ly/32cQHTF; reut.rs/34p4HHA)

Breast milk is not an unexpected source of COVID-19 transmission

Transmission of novel coronaviruses in newborns via breast milk is not possible, a new study indicates. Researchers analyzed 64 breast milk samples from 18 infected mothers. One sample contained virus-inactivated genetic material, but none of the samples contained active virus particles, researchers reported Wednesday at JAMA. Even if breast milk is contaminated during pumping and handling, the virus is neutralized by solder pasteurization, a standard procedure in human milk banks that involves heating the milk to a certain temperature and then cooling it. In theory, the mothers themselves could have done so, but “recommended good hygiene” is the best way to study the University of California co-author Lars Bode, San Diego told Reuters. The US Center for Disease Control and Prevention has advised nursing mothers to confirm potential or COVID-19 that the baby should be covered with a cloth while breastfeeding and that the baby and any parts of the pump or bottle are touched One must wash hands first. (Bit.ly/31fGoPa)

Maintain indoor humidity to limit aerial coronaviruses

According to a new study, reducing the presence of infectious viral droplets in the air will help keep the airborne transmission of novel coronaviruses between 40% and 60%. The authors stated that as the amount of water vapor in the air increases, the size of the viral droplet increases and the heavier droplets fall more quickly from the air, giving other people less chance to breathe and become infected. is. Conversely, when humidity is low, virus-containing droplets dry up – but small infectious virus particles survive, float longer in the air and, depending on ventilation conditions, fly into the room, the researchers aerosol Said in the Journal and Air Quality Research. Dry air also dries the mucous membranes in the nose and makes them more permeable to viruses. Officials should include humidity factors in future indoor guidelines, with CSIR co-author Drs. Sumit Kumar Mishra – National Physical Laboratory in New Delhi said in a press statement. His team said that these findings are relevant not only in the cold weather season. Countries in tropical and warm climates should take care that indoor rooms are not drained by overcooling with air conditioning. (Bit.ly/32eAe15)

Michigan Hospital launches telehealth volunteering

“Virtual volunteering” was carried out by researchers in hospitals via telehealth, which previously voluntarily reduced pressure on medical staff, enhanced patient experiences, reduced the risk of viral infections and was common to patients and families. Was providing a sense of being, the researchers said on Thursday. Journal of Medical Humanities. They urge hospitals to adapt medical volunteers for the coronovirus epidemic by restructuring volunteer services and support networks for virtual platforms. For example, he said, many hospitals have volunteers who provide educational services. Currently, patients have lost access to these tutors. University of Michigan study co-author Zachary Pickel, who has tried to encourage virtual volunteering, told Reuters, “Recently, we have worked with several departments of Michigan Hospital to provide assistance to patients and families Started a virtual volunteer program. ” With hospital staff. Our initial implementation enhanced engagement and positive attitudes. “(Bit.ly/2Qc4TGD)

Open tmsnrt.rs/3a5EyDh in an external browser for a Reuters graphic on treatments in vaccines and development.

Reporting by Nancy Lapid; Editing by Will Dunham

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