according to this The washington postThis research will begin in January, led by scientists Funded by Imperial College London and the British Government.
More than 100 volunteers between the ages of 18 and 30 will have strain developed in their nose in the laboratory of COVID-19 and will be quarantined in a private unit at the Royal Free Hospital in London, where they will undergo regular tests. For a period of two to three weeks.
According to the Post, the aim of the study is to determine the minimum number of viruses required to cause active infection in the upper respiratory tract of volunteers.
Later in the spring, scientists hope to add more volunteers, who will be treated with candidate vaccines and then exposed to the virus on how well the vaccines protect them.
Andrew Catchpole, chief science officer for HVIVO, a commercial pharmaceutical company that will coordinate human challenge test research, said the study was reviewed by a specially convened ethics committee and the UK’s Medicines and Healthcare Products Regulatory Agency, US Food and its Will be done by version. Drug Administration (FDA).
Trials of the challenge have not received widespread widespread support in the US, due to ethical concerns with those intentionally infected with the virus, which have already killed more than 1.1 million people globally. New York Times Coronavirus Database.
However, the idea of using challenge tests to speed up the process of vaccine testing has gained increasingly more ground.
In April, A group of 35 House MPs, Led by Reps. Bill fosterGeorge (Bill) William Fosterpelosi, Mnuchin continues to hold COVID-19 talks, hearing soon on CVID-19 efforts on Democrat press Azar amid dwindling barriers to deal, positive 81 DL soon after Trump test Laurets supported Biden’s White House bid (D-Ill.) And Donna shalalaDonna Edna Shalla is the ‘nodding woman’ behind Trump in the town hall. Former House candidate Shalla fixes Spicer on HIPAA: ‘I should know, I wrote it’ COVID-19 test positive in Capitol growth after Trump test positive (D-Fla.), A former Secretary of the Department of Health and Human Services, Wrote to FDA to articulate their support.
“Our position in this epidemic is in line with war, which has a long tradition of volunteers who risk their health and live on dangerous missions, for which they understand the risks and help to save the lives of others. Are willing to do it, “” he wrote in the letter.
in August, Reuters reported That federal health officials had begun preparatory work to establish a challenge test protocol for a COVID-19 vaccine, in which a strain of the virus could be manufactured.
The National Institute of Allergy and Infectious Diseases (NIAID) told Reuters at the time Several clinical studies of various vaccines were already underway, and a challenge test was unlikely to replace them.
Reuters said in August that NIAID was prioritizing large-scale field trials to evaluate COVID-19 vaccine candidates, while also being open to the possibility of using challenge tests for future generations of vaccines or treatments .
Challenge testing may help to approve a vaccine for public use as a conventional clinical trial compared to a conventional clinical trial Researchers will require that some participants wait to become infected during the daily lives.