Bacteria of gum disease linked to esophageal cancer – tech2.org

Bacteria of gum disease linked to esophageal cancer



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By: IANS | New York |

Published: December 3, 2017, 4:56 pm


Esophageal cancer is the eighth most common cancer and the sixth leading cause of death from cancer worldwide. (Source: Stock Photo)

Now there's another reason to brush your teeth regularly. Researchers have discovered that some bacteria that lead to gum disease can also increase the risk of esophageal cancer affecting the tube that runs from the throat to the stomach.

This study, published in the journal Cancer Research, examined whether oral microbiota was badociated with subsequent risk of esophageal cancer.

Tracing the oral health of 122,000 people in the US UU For a decade, the researchers found that two species of bacteria related to common gum disease can increase the risk of cancer.

Esophageal cancer is the eighth most common cancer and the sixth leading cause of cancer death worldwide, said one of the researchers Jiyoung Ahn, Associate Professor, New York University School of Medicine.

Because the disease is often not discovered until it reaches an advanced stage, five-year survival rates range between 15 and 25 percent worldwide.

"Oesophageal cancer is a highly deadly cancer, and there is an urgent need for new prevention pathways, risk stratification and early detection," Ahn said.

The most common types of esophageal cancer are esophageal adenocarcinoma (EAC) and esophageal squamous cell carcinoma (ESCC).

The researchers found that the highest levels of the Tannerella forsythia bacteria were badociated with a 21 percent increased risk of CAD.

The bacterium Porphyromonas gingivalis was badociated with an increased risk of ESCC.

Both species of bacteria are related to common gum disease, Ahn noted.

The study also showed that some types of oral bacteria were badociated with a lower risk of esophageal cancer.

For example, the Neisseria bacteria was badociated with a lower risk of CAD.

The finding in Neisseria indicates that certain bacteria may have a protective effect, and future research could potentially examine whether these bacteria could play a role in the prevention of esophageal cancer, Ahn said.

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