At least six months in a kind of immune coronovirus, the final phase of the study


Blood samples were to be tested for Kovid-19 antibodies at a clinic in Moscow on May 15, 2020

Blood samples were to be tested for Kovid-19 antibodies at a clinic in Moscow on May 15, 2020
Photo: Vasily Maximov (Getty Images)

This week’s new research can give some hope for at least one aspect of our immunity due to coronavirus-19. The study by researchers in the UK found evidence that some T cells made to counter coronovirus during infection showed a “strong” response at least six months later. This cellular immune response is thought to play an important role in reducing or reducing the severity of subsequent infection, along with other components of our immunity as antibodies.

New research work UK Coronavirus Immunology Consortium, A nationwide study supported by the UK government and involving several universities. As part of the project, researchers have tracked 100 volunteers who tested positive for antibodies to coronovirus sometime in March or April. Although some people developed symptoms at the time of their diagnosis, none required hospitalization.

T cells are one of the main cells of the immune system. They perform a wide assortment of duties during an infection, from directly killing infected cells to helping other cells perform their work better, including those proteins we call antibodies. Like antibodies, our body can produce T cells that specifically “miss” a previous pathogen and are capable of leaping into action when we try to rein in it. Compared to studying how germs react to a germ, however, a person’s cellular immune response is more complex and harder to measure. This makes this study the most important and the largest of its kind.

preliminary results, Released In a paper on the preprint website Biorexiv on Tuesday, looks decidedly encouraging. Researchers found that volunteers soon developed T cells for the virus. And when the volunteers’ blood was studied six months later, these T cells remained in their system.

“According to our knowledge, our study lasts six months to show the first cellular immunity in the world, which is either mild / moderate or asymptomatic,” said Paul Moss, a hematologist at the University of Birmingham. Chief Scientist of the project, A. Statement Released on Tuesday by the consortium.

Immunity to disease like Kovid-19, as we have discussed First, there is a complicated mess. Some research has suggested that coronovirus-specific antibodies may go away in at least three months, yet other research has suggested that the most important antibodies – which directly prevent the virus from infecting new cells – are at least Most can be sustained in survivors for less. five months. And still have other parts of the immune system relevant to Kovid-19 Which has not been studied very Detailed, Such as Memory B Sales.

Experts expect our natural immunity to coronoviruses, ultimately based on our history with other coronaviruses that make us sick (how vaccine-induced immunity will work is still uncertain). But the findings of this new study and others suggest that conservation at some levels should last more than a few months. This protection does not necessarily prevent recidivism in all cases (in fact, we are starting to see scattered cases of restitution. Reported Worldwide), but it will blunt the effects of a second infection if it does, experts have told Gizmodo.

There is still much about our immune response to understanding Kovid-19, and the findings of this study will provide scientists with new breadcrumbs to follow.

For example, the study found that people who felt ill had a stronger T-cell response than those who were asymptomatic, which could indicate that symptomatic survivors are better protected. People’s levels of T-cell response over time also strongly correlated their levels of antibodies to the virus, whereas initially a large T-cell response was associated with slower degradation of antibodies. This means that any future vaccines have to provoke a strong T-cell response in addition to an antibody response to be as effective as possible.

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