A British study found that type 2 diabetes could be reversed by losing weight and with the long-term support of a medical professional.
The initial findings come from an ongoing study called DiRECT (Diabetes Remission Clinical Trial), which aims to find an effective and accessible way to put type 2 diabetes in long-term remission.
Directed by Prof. Roy Taylor of the University of Newcastle and Prof. Mike Lean of the University of Glasgow, the study recruited 298 people and gave their primary care physician half of diabetes care, while that the other half was assigned a structured weight control program that included a diet low in calories and nutrients for three to five months, reintroduction of food and long-term support to maintain weight loss.
The team found that remission of diabetes was closely related to weight loss, with nearly nine in 1
Ove Half (57%) of those who lost between 10 and 15 kg also achieved remission, along with one third (34%) of those who lost 5 to 10 kg.
In comparison, only 4% of the control group, who received standard care, achieved remission.
Prof. Taylor commented on the results of the first year saying: "These findings are very exciting, they could revolutionize the way type 2 diabetes is treated."
"The study is based on work on the underlying cause of the condition, so that we can The substantial loss of weight results in a reduction of fat within the liver and pancreas, allowing these organs to return to Normally, what we are seeing from DiRECT is that losing weight is not only related to better control of type 2 diabetes: significant weight loss could result in a lasting remission. "
Type 2 diabetes is a life-changing condition that progresses over time with potentially devastating consequences.
Remission could transform the lives of millions of people living at risk for the condition, which reduces the risk of developing serious complications, such as cardiovascular disease, kidney disease or stroke.
DiRECT is a two-year trial, with Dr. Elizabeth Robertson, Director of Research at Diabetes UK, commenting that "we are very encouraged by these initial results and by the strong evidence that remission could be achieved for some people".
"The trial is underway, so we can understand the long-term effects of an approach like this.It is very important that anyone living with type 2 diabetes who is losing weight seek support and advice from a professional health ".
The results can be found published online in The Lancet.